Predicting DNA-binding Specificities for Cys2His2 Zinc Finger Proteins
A DNA binding site predictor for Cys2His2 Zinc Finger Proteins
Welcome to our new site!
For a given C2H2 zinc finger protein, we predict a position weight matrix representing its DNA binding specificity and display it as a sequence logo. This result can be used further to search genomic sequences for putative binding sites.
This site serves as an interface between a user's input and a set of prediction algorithms that are able to create the mentioned logos. It consists of a protein input screen, followed by the selection of the desired set of fingers, and the algorithm to be used. The results are delivered through a simple HTML page that contains the generated sequence logo.